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Tripti Gupta

Research Associate

Tripti Gupta

    tgupta@fas.harvard.edu
     

As a graduate student and postdoc, my research interests focused on understanding the genetic and molecular mechanisms required for development of the oocyte and egg. Prior to joining the Extavour lab, I studied follicle cell patterning in Drosophila and establishment of oocyte polarity in zebrafish. Recently, I have become interested in understanding the mechanisms by which the germline is specified, in particular within an evolutionary biology context. My current project focuses on germline development in the crustacean Parhyale hawaiensis.

Publications

Gupta, T., Zeng, V., Alwes, F., Linsler, F., and Extavour, C.G. RNA-Seq Analysis of germ line regeneration in the crustacean Parhyale hawaiensis. In preparation.

Sharma, P.P., Schwager E. E., Gupta, T. Wheeler, W., and Extavour, C.G. Homology of deutocerebral appendages revealed by functional interrogation of homothorax in the harvestman Phalangium opilio. In preparation.

Ge, X., Grotjahn, D., Welch, E., Holguin, C., Lyman-Gingerich, J., Dimitrova, E., Abrams, E.W., Gupta, T., Marlow, F.L., Yabe, T., Adler, A., Mullins, M.C., Pelegri, F. Hecate/Grip2a acts to reorganize the cytoskeleton in the symmetry-breaking event of embryonic axis induction. PLoS Genetics, submitted.

Sharma, P.P., Gupta, T., Schwager, E.E., Wheeler, W., and Extavour C.G. (2014) Subdivision of arthropod cap-n-collar expression domains is restricted to Mandibulata. EvoDevo 5(1): 3.

Gupta, T. and Extavour, C.G. (2013) Identification of a putative germ plasm in the crustacean Parhyale hawaiensis. EvoDevo 4(1):34.

EauClaire, S.F., Cui, S., Ma, L., Matous, J., Marlow F.L., Gupta, T., Burgess, H.A., Abrams, E.W., Kapp, L.D., Granato, M., Mullins, M.C., and Matthews, R.P. (2012) Mutations in vacuolar H+-ATPase subunits lead to biliary developmental defects in zebrafish. Developmental Biology, 365(2): 434-444.

Gupta, T., Marlow, F., Ferriola, D., Mackiewicz, K., Dapprich, J., Monos, D., and Mullins, M.C. (2010) Microtubule Actin Crosslinking Factor 1 Regulates Balbiani Body Function and Animal-Vegetal Polarity of the Zebrafish Oocyte. PLoS Genetics, 6(8):e1001073.

Gupta, T. and Mullins, M.C. (2010) Dissection of Organs from the Adult Zebrafish.  Journal of Visualized Experiments, 37. doi: 10.3791/1717.

Bontems, F., Stein, A., Marlow, F., Lyautey, J., Gupta, T., Mullins, M.C., Dosch R. (2009) Bucky ball Organizes Germ Plasm Assembly in Zebrafish. Current Biology, 19(5): 414-422.

Alvarez-Delfin, K., Morris, A.C., Snelson, C.D., Gamse, J.T., Gupta, T., Marlow, F.L., Mullins, M.C., Burgess, H.A., Granato, M., Fadool, J.M. (2009) Tbx2b is Required for Ultraviolet Photoreceptor Cell Specification During Zebrafish Retinal Development. Proceedings of the National Academy of Sciences, 106(6): 2023-2028.

Gupta, T. and Schupbach, T. (2003)  Cct1, a Phosphatidylcholine Biosynthesis Enzyme, is Required for Drosophila Oogenesis and Ovarian Morphogenesis Development, 130(24): 6075-6087.

Gupta, T. and Schupbach, T. (2001)  Two Signals are Better Than One. Developmental Cell, 1(4): 443-445.