Ed Pym

Ed Pym

Research Associate
edward_pym@fas.harvard.edu


Education:

B.Sc. (Honours) in Microbiology and Virology. University of Warwick, Warwick, UK
Ph.D. in Neurobiology. University of Warwick, Warwick, UK

Other Publications:

López-Rivera F, Foster Rhoades OK, Vincent BJ, Pym ECG, Bragdon MDJ, Estrada J, DePace AH, Wunderlich Z. A Mutation in the Drosophila melanogaster eve Stripe 2 Minimal Enhancer Is Buffered by Flanking Sequences. G3 (Bethesda). 2020 Dec 3;10(12):4473-4482. doi: 10.1534/g3.120.401777. PMID: 33037064.

Vincent BJ, Staller MV, Lopez-Rivera F, Bragdon MDJ, Pym ECG, Biette KM, Wunderlich Z, Harden TT, Estrada J, DePace AH. Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos. PLoS Genet. 2018 Sep 7;14(9):e1007644. doi: 10.1371/journal.pgen.1007644. PMID: 30192762.

Pym, E. C. G., Sasidharan, N., Thompson-Peer, K. L., Simon, D. J., Anselmo, A., Sadreyev, R., Hall, Q., Nurrish, S., & Kaplan, J. M. (2017). Shank is a dose-dependent regulator of Cav1 calcium current and CREB target expression. Elife, May 6;6. pii: e18931. doi: 10.7554/ eLife.18931.

Younger, M. A., Müller, M., Tong, A., Pym, E. C. G., & Davis, G.W. (2013). A presynaptic ENaC channel drives homeostatic plasticity. Neuron, 79(6), 1183-96

Hu, Z.*, Pym, E. C. G*., Babu, K*., Vashlishan Murray*, A. B., & Kaplan, J. M. (2011). A neuropeptide mediated stretch response links muscle contraction to changes in neurotransmitter release. Neuron, 71(1), 92–102.*joint first

Müller, M., Pym, E. C. G., Tong, A., & Davis, G. W. (2011). Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle release. Neuron, 69(4), 749– 762.

Bai, J., Hu, Z., Dittman, J. S., Pym, E. C. G., & Kaplan, J. M. (2010). Endophilin functions as a membrane bending molecule and is delivered to endocytic zones by exocytosis. Cell, 143(3), 430–441.

Marie, B., Pym, E. C. G., Bergquist, S., & Davis, G. W. (2010). Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog. The Journal of Neuroscience, 30(24), 8071 8082.

Pym, E. C. G., Southall, T. D., Mee, C. J., Brand, A. H., Baines, R. A. (2006). The homeobox transcription factor Even-skipped regulates acquisition of electrical properties in Drosophila neurons. Neural Develop. 2006 Nov 16;1:3.

Baines, R. A. and Pym, E. C. G. (2006). Determinants of electrical properties in developing neurons. Semin. Cell Dev. Biol. 2006 Feb;17(1):12-9.

Mee, C. J., Pym, E. C. G. , Moffat, K. G., and Baines, R. A. (2004). Regulation of neuronal excitability through translational control of a sodium channel gene. J Neurosci. 2004: 24(40):8695-8703.