Publications 2020

Adaptation of codon and amino acid use for translational functions in highly expressed cricket genes. Whittle, C.A., Kulkarni, A., Chung, N. and Extavour, C.G. bioRxiv, doi: (2020). [PubMed]
Topology-driven analysis of protein-protein interaction networks detects functional genetic modules regulating reproductive capacity. Kumar, T., Blondel, L. and Extavour, C.G. eLife, (in press) (2020). [PubMed]
Shared cell biological functions may underlie pleiotropy of gene regulatory modules in the germ lines and nervous systems of animals. Kulkarni, A., Lopez, D., and Extavour, C.G. Frontiers in Ecology and Evolution, doi: 10.3389/fevo.2020.00215 (2020). [PubMed]
Sex-biased genes expressed in the cricket brain evolve rapidly. Whittle, C.A., Kulkarni, A. and Extavour, C.G. bioRxiv, (2020). [PubMed]
Cricket genomes: the genomes of future food. Ylla G., Nakamura T., Itoh T., Kajitani R., Atsuhi T., Sayuri T., Tetsuya B., Yoshiyasu I., Watanabe T., Fuketa M., Matsuoka Y., Noji S., Mito T. and Extavour C.G. bioRxiv, (2020). [PubMed]
Repeated loss of variation in insect ovary morphology highlights the role of developmental constraint in life-history evolution. Church, S.H., de Medeiros, B.A.S., Donoughe, S.D., Marquez Reyes, N.L. and Extavour, C.G. bioRxiv, (2020). [PubMed]
Null hypotheses for developmental evolution. Church, S.H. and Extavour, C.G. Development, 147, dev178004 (2020). [PubMed]
Absence of a faster-X effect in beetles (Tribolium, Coleoptera). Whittle, C.A., Kulkarni, A. and Extavour, C.G.* G3: Genes, Genomes, Genetics, doi:10.1534/g3.120.401074 (2020). [PubMed]
Bacterial contribution to genesis of the novel germ line determinant oskar. Blondel, L., Jones, T.E.M. and Extavour, C.G. eLife, 9:e45539 (2020).

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Publications 2019

Evidence of multifaceted functions of codon usage in translation within the model beetle Tribolium castaneum. Whittle, C.A., Kulkarni, A. and Extavour, C.G.* DNA Research, 26(6): 473-484 (2019). [PubMed]
Chapter 8: The Cricket Gryllus bimaculatus: Techniques for Quantitative and Functional Genetic Analyses of Cricket Biology. Kulkarni, A.* and Extavour, C.G.* Results and Problems in Cell Differentiation, Volume 68: Evo-Devo: Non-model Species in Cell and Developmental Biology (edited by Waclaw Tworzydlo and Szczepan M. Bilinski), 68:183-216 (2019). [PubMed]
A dataset of egg size and shape from more than 6,700 insect species. Church, S.H.*, Donoughe, S.D., de Medeiros, B.A.S. and Extavour, C.G. Scientific Data, 6:104 (2019). [PubMed]
Hox genes limit germ cell formation in the short germ insect Gryllus bimaculatus. Barnett, A.A., Nakamura, T. and Extavour, C.G.* PNAS, 116(33):16430-16435 (2019). [PubMed]
Reproductive Capacity Evolves in Response to Ecology through Common Changes in Cell Number in Hawaiian Drosophila. Sarikaya, D.P.*, Church, S.H., Lagomarsino L.P., Magnacca K.M., Montgomery S.L., Price D.P., Kaneshiro K.Y. and Extavour C.G.* Current Biology, 29(11): 1877-1884 (2019).

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Injecting Gryllus bimaculatus Eggs. Barry, S, Nakamura, T., Matsuoka, Y., Straub, C., Horch, H.W.* and Extavour, C.G. JoVE, (150): doi: 10.3791/59726 (2019). [PubMed]
Ancestral and offspring nutrition interact to affect life history traits in Drosophila melanogaster. Deas, J.B.*, Blondel, L. and Extavour, C.G.* Proceedings of the Royal Society B, 286(1897):20182778 (2019). [PubMed]
Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome. Panfilio, K.A.*, Vargas Jentzsch, I.M., Benoit, J.B., Erezyilmaz, D., Suzuki, Y., Colella, S., Robertson, H.M., Poelchau, M.F., Waterhouse, R.M. Ioannidis, P. Weirauch, M.T., Hughes, D.S.T., Murali, S.C., Werren, J.H., Jacobs, G.C.G., Duncan, E.J., Armisén, D., Vreede, B.M.I., Baa-Puyoulet, P., Berger, C.S., Chang, C.-C., Chao, H., Chen, M.-J.M. , Chen, Y.-T., Childers, C.P., Chipman, A.D., Cridge, A.G., Crumire, A.J.J., Dearden, P.K., Didion, E.M., Dinh, H., Doddapaneni, H., Dolan, A., Dugan, S., Extavour, C.G., Febvay, G., Friedrich, M., Ginzburg, N., Han, Y., Heger, P., Horn, T., Hsiao, Y.-M., Jennings, E.C., Johnston, J.S., Jones, T.E. M., Jones, J.W., Khila, A., Koelzer, S., Kovacova, V., Leask, M., Lee, S.L., Lee, C.-Y.,Lovegrove, M.R., Lu, H.-L. Lu, Y. Moore, P.J., Munoz-Torres, M.C., Muzny, D.M., Palli, S.R., Parisot, N. Pick, L., Porter, M., Qu, J., Refki, P.N., Richter, R.,Rivera Pomar, R., Rosendale, A.J., Roth, S., Sachs, L., Santos, M.E., Seibert, J., Sghaier, E., Shukla, J.N.,Stancliffe, R.J., Tidswell, O., Traverso, L., van der Zee, M., Viala, S., Worley, K.C., Zdobnov, E.M., Gibbs, R.A., Richards, S.* Genome Biology, 20(1):64 (2019). [PubMed]
Contrasting patterns of molecular evolution in metazoan germ line genes. Whittle, C.A. and Extavour, C.G.* BMC Evolutionary Biology, 19(1):53 (2019). [PubMed]
Selection shapes turnover and magnitude of sex-biased expression in Drosophila gonads. Whittle, C.A. and Extavour, C.G.* BMC Evolutionary Biology, 19(1):60 (2019). [PubMed]

Publications 2018

High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system. Donoughe, S.D., Kim, C. and Extavour, C.G. Biology Open, 7(7) pii: bio.031260 (2018). [PubMed]

Publications 2017

The house spider genome reveals an ancient whole-genome duplication during arachnid evolution. Clarke, T., Schwager, E.E., Sharma, P.P., Wierschin, T., Pechmann, M., Akiyama-Oda, Y., Arensburger, P., Bucher, G., Buffry, A., Chao, H., Dinh, H., Doddapaneni, H., Dugan, S., Eibner, C., Extavour, C.G., Garb, J., Griffiths-Jones, S., Han, Y., Hayashi, C., Hilbrant, M., Hughes, D.S.T., Janssen, R., Lee, S.L., Leite, D.J., Murali, S.C., Muznym D.M., Nunes da Fonseca, R., Qu, J., Ronshaugen, M., Schomburg, C., Schönauer, A., Stollewerk, A., Torres-Oliva, M., Turetzek, N., Wolff, C., Worley, K.C., Gibbs, R.A., Coddington, J., Damen, W.G.M, Oda, H., Stanke, M., Ayoub, N., Prpic, N.-M., Posnien, N., Richards, S. and McGregor, A.P. BMC Biology, 15(1): 62 (2017). [PubMed]
Expression and function of spineless orthologs correlate with distal deuterocerebral appendage morphology across Arthropoda. Setton, E.V.W., March, L.W., Nolan, E.D., Jones, T.E., Cho, H., Wheeler, W.C., Extavour, C.G. and Sharma, P.P. Developmental Biology, 430(1): 224-236 (2017). [PubMed]
Convergent evolution of germ granule nucleators: a hypothesis. Kulkarni, A. and Extavour, C.G. Stem Cell Research, 24: 188-194 (2017). [PubMed]
Rapid evolution of ovarian-biased genes in the yellow-fever mosquito (Aedes aegypti). Whittle, C.A. and Extavour, C.G. Genetics, 206(4): 2119-2137 (2017). [PubMed]
Bone Morphogenetic Protein (BMP) signaling in animal reproductive system development and function. Lochab, A.K. and Extavour, C.G. Developmental Biology, 427(2): 258-269 (2017). [PubMed]
Causes and evolutionary consequences of primordial germ cell specification mode in metazoans. Whittle, C.A. and Extavour, C.G. Proceedings of the National Academy of Sciences of the USA, 114(23): 5784-5791 (2017). [PubMed]

Publications 2016

The genome of Parhyale hawaiensis: a model for animal development regeneration, immunity and ligno-cellulose digestion. Kao, D., Lai, A., Stamataki, E., Rosic, S., Konstantinides, N., Jarvis, E., Di Donfrancesco, A., Pouchkina-Stancheva, N., Semon, M., Grillo, M., Bruce, H., Kumar, S., Siwanowicz, I., Le, A., Lemire, A., Extavour, C.G., Browne, W., Wolff, C., Averof, M., Patel, N.H., Sarkies, P., Pavlopoulos, A. and Aboobaker, A. eLife 5, e200629 (2016). [PubMed]
Editorial Overview: Developmental mechanisms, patterning and evolution: New models for genetics and development – diversity at last. Arendt, D. and Extavour, C.G. Current Opinion in Genetics and Development, 39 iv-vi (2016). [PubMed]
Refuting the hypothesis that the acquisition of germ plasm accelerates animal evolution. Whittle, C.A. and Extavour, C.G. Nature Communications, 7, 12637 (2016). [PubMed]
A premeiotic function for boule in the planarian Schmidtea mediterranea. Iyer, H., Issigonis, M., Sharma, P.P., Extavour, C.G. and Newmark, P.A. PNAS, 113(25): E3509-18 (2016). [PubMed]
Expression-linked patterns of codon usage, amino acid frequency and protein length in the basally branching arthropod Parasteatoda tepidariorum. Whittle, C.A. and Extavour, C.G. Genome Biology and Evolution, 8(9) 2722-36 (2016). [PubMed]
Editorial Overview: Development, regulation and evolution of organ systems. Extavour, C.G. and Pick, L. Current Opinion in Insect Science, do13: vii-ix (2016). [PubMed]

Publications 2015

The transcriptional repressor Blimp-1 acts downstream of BMP signaling to generate primordial germ cells in the cricket Gryllus bimaculatus.. Nakamura, T. and Extavour, C.G. Development 143(2), 255-263 (2016). [PubMed]
vasa and piwi are required for mitotic integrity in early embryogenesis in the spider Parasteatoda tepidariorum. Schwager, E.E., Meng, Y. and Extavour, C.G. Developmental Biology, 402(2): 276-290 (2015). [PubMed]
Codon and amino acid usage are shaped by selection across divergent model organisms of the Pancrustacea. Whittle, C.A. and Extavour, C.G. G3: Genes, Genomes, Genetics, 5(11) 2307-2321 (2015). [PubMed]
The significance and scope of evolutionary developmental biology: a vision for the 21st century. Moczek, A., Sears, K., Stollewerk, A., Wittkopp, P., Diggle, P., Dworkin, I., Ledon-Rettig, C., Matus, D., Roth, S., Abouheif, E., Brown, F. Chiu, C.-H., Cohen, C.S., De Tomaso, T., Gilbert, S., Hall, B., Love, A., Lyons, D., Sanger, T., Smith, J., Specht, C., Vallejo-Marin, M. and Extavour, C.G. Evolution and Development, 17(3): 198-219 (2015). [PubMed]
Embryonic development of the cricket Gryllus bimaculatus. Donoughe, S. and Extavour, C.G. Developmental Biology, 411(1): 140-156 (2015). [PubMed]
A conserved genetic mechanism specifies deutocerebral appendage identity in insects and arachnids. B. Sharma, P. P., Tarazona, O.A., Lopez, D.H., Schwager, E.E., Cohn, M.J., Wheeler, W.C. and Extavour, C.G. Biological Sciences, 282(1808) 20150698 (2015). [PubMed]
The Hippo pathway regulates homeostatic growth of stem cell niche precursors in the Drosophila ovary. Sarikaya, D.P. and Extavour, C.G. PLoS Genetics 11(2), e1004962 (2015).

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Publications 2014

The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima. Chipman, A.D., Ferrier, D.E.K and the Strigamia maritima sequencing and annotation consortium (105 authors, including C. G. Extavour (#26) and T. Jones (#49)). PLoS Biology, 12(11): e1002005 (2014). [PubMed]
A comprehensive reference transcriptome resource for the common house spider Parasteatoda tepidariorum. Posnien, N., Zeng V., Schwager, E.E., Pechmann, M., Hilbrant, M., Keefe, J., Damen, W.G.M., Prpic-Schaper, N., McGregor, A.P. and Extavour, C.G. PLoS ONE, 9(8): e104885 (2014). [PubMed]
Hox gene duplications correlate with posterior heteronomy in scorpions. Sharma, P.P., Schwager, E.E., Extavour, C.G. and Wheeler, W.C Proceedings of the Royal Society B: Biological Sciences, 281(1792): 20140661 (2014). [PubMed]
Ablation of a single cell from eight-cell embryos of the amphipod crustacean Parhyale hawaiensis.. Nast, A. R. and Extavour, C.G. Journal of Visualized Experiments, 16 March, 2014, Issue 85, doi:10.3791/51073 (2014). [PubMed]
Subdivision of arthropod cap-n-collar expression domains is restricted to Mandibulata. Sharma, P.P., Gupta, T., Schwager, E.E., Wheeler, W., and Extavour C.G EvoDevo, 5(1): 3 (2014). [PubMed]
BMP signaling is required for generation of primordial germ cells in an insect. Donoughe, S., Nakamura, T., Ewen-Campen, B., Green II, D.A., Henderson, L. and Extavour, C.G Proceedings of the National Academy of Sciences of the USA, 111(11): 4133-4138 (2014). [PubMed]
Insulin Signaling Underlies Both Plasticity and Divergence of a Reproductive Trait in Drosophila. Green II, D.A. and Extavour, C.G. Proceedings of the Royal Society B: Biological Sciences, 281(1779): 20132673 (2014).

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Patterns of molecular evolution of the germ line specification gene oskar suggest that a novel domain may contribute to functional divergence in Drosophila. Ahuja, A. and Extavour, C.G. Development, Genes and Evolution, 224(2): 65-77 (2014). [PubMed]

Publications 2013

Identification of a putative germ plasm in the crustacean Parhyale hawaiensis. Gupta, T. and Extavour, C.G. EvoDevo, 4(1): 34 (2013). [PubMed]
Live long and prosper: Germline stem cell maintenance revisited. Extavour, C.G BioEssays, 35(9): 763 (2013). [PubMed]
Evidence against a germ plasm in the milkweed bug Oncopeltus fasciatus, a hemimetabolous insect. Ewen-Campen, B.*, Jones, T.E.*. and Extavour, C.G. Biology Open, 2(6): 556-568 (2013). [PubMed]
Germ Cell Specification Requires Zygotic Mechanisms Rather Than Germ Plasm in a Basally Branching Insect. Ewen-Campen, B., Donoughe, S., Clarke, D.N., and Extavour, C.G Current Biology, 23(10): 835-842 (2013). [PubMed]
Distal-less and dachshund pattern both plesiomorphic and derived structures in chelicerates: RNA interference in the harvestman Phalangium opilio.. Sharma, P.P., Schwager, E.E., Giribet, G.G., Jockusch, E. and Extavour, C.G Evolution and Development, 15(4): 228-242 (2013). [PubMed]
Developmental Gene Discovery in a Hemimetabolous Insect: De Novo Annotation and Assembly of a Transcriptome for the Cricket Gryllus bimaculatus. Zeng, V. Ewen-Campen, B., Horch, H.W., Roth, S., Mito, T. and Extavour, C.G. PLoS ONE, 8(5): e61479 (2013). [PubMed]

Publications 2012

oskar Predates the Evolution of Germ Plasm in Insects. Ewen-Campen, B., Srouji, J.R., Schwager, E.E. and Extavour, C.G. Current Biology, 22(23): 2278-2283 (2012).

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Evolution of the chelicera: a dachshund domain is retained in the deutocerebral appendage of Opiliones (Arthropoda, Chelicerata). Sharma, P.P., Schwager, E.E., Extavour, C. G. and Giribet, G Evolution and Development, 14(6): 522-533 (2012). [PubMed]
ASGARD: an open-access database of annotated transcriptomes for emerging model arthropod species. Zeng, V. and Extavour, C.G Database, 10.1093/database/bas048 (2012).

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Hox gene expression in the harvestman Phalangium opilio reveals divergent patterning of the chelicerate opisthosoma. Sharma, P.P., Schwager, E.E., Extavour, C. G. and Giribet, G. Evolution and Development, 14(5): 450-463 (2012). [PubMed]
Convergent evolution of a reproductive trait through distinct developmental mechanisms in Drosophila. Green II, D.A. and Extavour, C.G. Developmental Biology, 372(1): 120-130 (2012). [PubMed]

Publications 2011

The roles of cell size and cell number in determining ovariole number in Drosophila. Sarikaya, D.P., Belay, A.A., Ahuja, A., Green II, D.A., Dorta, A. and Extavour, C.G. Developmental Biology, 363(1): 279-289 (2012). [PubMed]
De novo assembly and characterization of a maternal and developmental transcriptome for the emerging model crustacean Parhyale hawaiensis. Zeng, V., Villanueva, K.E., Ewen-Campen, B., Alwes, F., Browne, W.E. and Extavour, C.G. BMC Genomics, 12(1): 581 (2011). [PubMed]
Notch/Delta signalling is not required for segment generation in the basally branching insect Gryllus bimaculatus. Kainz, F., Ewen-Campen, B., Akam, M. and Extavour, C.G. Development, 138(22): 5015-5026 (2011). [PubMed]
Patterns of cell lineage, movement, and migration from germ layer specification to gastrulation in the amphipod crustacean Parhyale hawaiensis. Alwes, F., Hinchen, B. and Extavour, C.G. Developmental Biology, 359(1): 110-123 (2011). [PubMed]
Long-Lost Relative Claims Orphan Gene: oskar in a Wasp. Extavour, C.G. PLoS Genetics, 7(4): e1002045 (2011). [PubMed]
Counting in oogenesis. Green, D.A.*, Sarikaya, D.P.* and Extavour, C.G Cell and Tissue Research, 344(2): 207-212 (2011). [PubMed]
The maternal and early embryonic transcriptome of the milkweed bug Oncopeltus fasciatus. Ewen-Campen, B., Shaner, N., Panfilio, K., Suzuki, Y., Roth, S. and Extavour, C.G. BMC Genomics, 12(1): 61 (2011). [PubMed]

Publications 2010

Redefining stem cells and assembling germ plasm: key transitions in the evolution of the germ line. Srouji, J.R. and Extavour, C.G Science Publishers, Chapter 16, pp. 360-397 in Key Transitions in Animal Evolution, R. DeSalle and B. Schierwater, eds. CRC Press, Taylor & Francis Group.

Publications 2009

The molecular machinery of germ line specification. Ewen-Campen, B., Schwager, E.E., Extavour, C.G Molecular Reproduction and Development, 77(1): 3-18 (2010). [PubMed]
Oogenesis: Making the Mos of Meiosis. Extavour, C.G Current Biology, 19(12): R489-R491 (2009). [PubMed]

Publications 2008

Urbilaterian Reproduction: the evolution of metazoan germ cell specification mechanisms. Extavour, C.G Chapter 17, pp. 321-342 in Evolving Pathways: Key Themes in Evolutionary Developmental Biology, Alessandro Minelli and Giuseppe Fusco, eds. Cambridge University Press (2008).

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Are We There Yet? Tracking the Development of New Model Systems. Abzhanov, A., Extavour, C.G., Groover, A., Hodges, S., Hoekstra, H., Kramer, E M., Monteiro, A Trends in Genetics, 24(7): 353-360 (2008). [PubMed]
Vasa protein expression is restricted to the small micromeres of the sea urchin, but is inducible in other lineages early in development. Voronina, E., Lopez, M., Juliano, C. E., Gustafson, E., Song, J. L., Extavour, C.G., George, S., Oliveri, P., McClay, D., and Wessel, G Developmental Biology, 314(2): 276-286 (2008). [PubMed]

Publications 2007

Gray Anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Extavour, C.G Integrative and Comparative Biology, 47(3): 420-426 (2007).

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Evolution of the bilaterian germ line: lineage origin and modulation of specification mechanisms. Extavour, C.G Integrative and Comparative Biology, 47(5): 770-785 (2007). [PubMed]

Publications 2005

vasa and nanos expression patterns in a sea anemone and the evolution of bilaterian germ cell specification mechanisms. Extavour, C.G., Pang, K., Matus, D.Q. and Martindale, M.Q. Evolution and Development, 7(3): 201-215 (2005). [PubMed]

Publications 2004

Hold the germ cells, I’m on duty (on germ cell specification and caste determination in a polyembryonic wasp. Extavour, C.G BioEssays, 26(12): 1263-1267 (2004). [PubMed]
The fate of isolated blastomeres and formation of germ cells in the amphipod crustacean Parhyale hawaiensis. Extavour, C.G. Developmental Biology, 277(2): 387-402 (2005). [PubMed]
Not just a tasty snack: review of Evolutionary Developmental Biology of Crustacea, ed. G. Scholtz. Extavour, C.G. BioEssays, 26 (11): 1256-1258 (2004).

Publications 2003

Mechanisms of germ cell specification across the metazoans: epigenesis and preformation. Extavour, C.G. and Akam, M. Development, 130(24): 5869-5884 (2003).

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Publications 2001

Germ cell selection in genetic mosaics in Drosophila melanogaster. Extavour, C.G. and García-Bellido, A. Proceedings of the National Academy of Sciences of the USA, 98(20): 11341-11346 (2001). [PubMed]